13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... bone marrow and secondary ... #Hematology #Oncology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Differential Diagnosis Algorithm ... (ALL) • Acute ... (AML) • Chronic ... (CML) - Hemolytic ... Anemia - Others
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Neutropenia, anemia ... microglobulin Treatment ... #CLL #Chronic ... diagnosis #workup #oncology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... Myelodysplastic syndrome ... myeloid leukemia ... (CML) - Dr. ... #secondary
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... • Toxic Damage ... Leukemia, Tumour ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
• Eosinophilic Leukemia ... familial eosinophilia Secondary ... ), Heme malig (AML ... , CML, T-cell leuk ... insufficiency, Chronic
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
(dry skin) • Atopic ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #generalized #dermatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... 5) Symptoms of anemia ... uw_IMresidency #CLL ... #Leukemia #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... transformation to acute leukemia ... Allogeneic stem cell ... #hematology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Marrow Failure • Chronic ... (CML) • Felty ... Cell Leukemia ... #oncology