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hematology management differential oncology algorithm syndrome table classification dermatology lupus summary thrombocytosis arthritis clinical cll deficiency druginduced hodgkins lymphocytic lymphoma
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... -> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... #Hematology #Oncology ... #Diagnosis
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
- Differential Diagnosis ... (AML) • Chronic ... Renal • Chronic ... #Differential #Diagnosis ... endocrinology #causes
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
- Differential Diagnosis ... Myelofibrosis • Chronic ... Myeloid Leukemia ... #Differential #Diagnosis ... #causes #Platelets
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome - Causes ... and Treatment ... Hydroxyurea - Leukemia ... hyperleukocytosis (AML ... #Differential #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Myelogenous Leukemia ... effect following treatment ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... myeloid leukemia ... (CML) - Dr. ... #Causes #hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... - Differential Diagnosis ... Myeloproliferative Disorder • Chronic ... #Algorithm #Causes ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Age > 50 • Chronic ... #Algorithm #Causes ... #Hematology #Oncology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... Disorders: • Chronic ... (CML) - associated ... #Differential #Diagnosis ... #causes #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... Primary: - CML ... Hypereosinophilic Syndrome - Chronic ... #Causes #hematology
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