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diagnosis hematology management causes oncology algorithm syndrome clinical nephrology dermatology endocrinology pathophysiology allergy auer auerrods basophils blood bloodsmear cancer chronic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... leukemias > 20% ... Chronic leukemia ... Neutrophils • Immature/Myeloblasts ... cutaneous plaques) AML
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... acute myelogenous leukemia ... (AML) that is most ... Rods #AuerRods #AML
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Syndrome - Causes and Treatment ... Plasmapheresis - Leukemia ... Hydroxyurea - Leukemia ... hyperleukocytosis (AML ... Syndrome #Causes #Differential
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Myeloid Leukemia ... (AML) • Chronic ... Myeloid Leukemia ... Hyperuricemia #Differential
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytic leukemia ... hospitalization and treatment ... acute myeloid leukemia ... (AML) t(8;21), ... mixed lineage leukemia
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 Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
cells within the myeloblast ... Leukemoid reaction ... part automated differential ... Leukemoid Reaction ... D/D leukemia: increases
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Treatment Schema ... Lymphoblastic Leukemia ... Cytarabine #ALL ... Lymphoblastic #Leukemia ... #Treatment #timeline
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Chronic myeloid leukemia ... (CML) - associated ... Acute myeloid leukemia ... #Basophilia #Differential
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Burkitt's lymphoma & ALL ... spontaneously (before any treatments ... lymphoma & Acute leukemia ... (both ALL and AML ... malignancies Treatments
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - Differential ... Ovarian - Leukemia ... Lymphoma: NHL, CML ... Hypercalcemia #Differential
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