8 results
hematology algorithm causes wbc anemia blood cbc hemolytic leukemoid leukocytosis markers neutrophil oncology pathophysiology secondary testing workup
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Basophils < ... released during an allergic ... Myeloproliferative Disorders ... #hematology #basophils
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Diagnosis Secondary ... malignancies • Anemia ... Chronic inflammatory disorders ... Chronic myeloid leukemia
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... hepatomegaly • Labs: anemia ... after initial Rx), basophilia ... #hematology #WBC ... #Leukemoid
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Diagnosis Algorithm ... Chronic Myelogenous Leukemia ... • Rheumatic disorders ... #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... #hematology #Markers ... #Differential # ... Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... thalassemia, S Lepore • Basophilic ... DIC, TTP, HELLP, HUS ... Consider RBC membrane disorder
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
eosinophilia, basophilia ... , and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Cell population has ... on the left Myeloblast ... Tissue damage • Leukemia ... #differential # ... #WBC #CBC #hematology
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