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hematology oncology algorithm management myelodysplastic anemia aplastic blood cellulitis disorders eosinophilia markers mimickers mimics platelets pseudocellulitis secondary skin syndromes treatment
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... Chronic myeloid leukemia ... Diagnosis #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... old, ~10,000 new cases ... transformation to acute leukemia ... #Syndrome #MDS
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Disorders - Myelodysplastic ... - Amy Chung, MD ... #Diagnosis #Algorithm
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- Differential ... Diagnosis Bugs: ... Hypereosinophilic Syndrome ... #Diagnosis #Causes ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... blood count with differential ... #Syndromes #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Kawasaki, Nephrotic syndrome ... post-splenectomy, Exercise, Allergic ... Matthew Ho, MD
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... basophilia, and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... • Tumor lysis syndrome ... #Diagnosis
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics Cellulitis: Deep skin and subcutaneous fat infection Pseudo
- Differential ... antibiotics and avoid allergic ... • Lymphoma • Leukemia ... • Compartment syndrome ... #dermatology #skin
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • Hypocellular myelodysplastic ... syndrome (MDS) ... virus (EBV) • Leukemia ... #diagnosis #management
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