18 results
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Is visual loss caused ... Doppler US : halo sign ... #Rheumatology # ... Ophthalmology #Diagnosis ... #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... HUS • DIC • Vasculitis ... #Algorithm #Causes ... #Hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... (5%): PAN > GPA ... #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... -> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... #Hematology #Oncology ... #Diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Symptomatic anemia Diagnosis ... to MDS or acute leukemia ... management #treatment #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology # ... classification
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... = vasculitis vs ... them, but urgent rheumatology ... #Temporal #Signs ... #Symptoms #Diagnosis
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
commonly hairy-cell leukemia ... Viral replication causes ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... #diagnosis #workup ... #oncology #hematology