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oncology differential workup causes leukemia aplastic chronic cll lymphocytic mds myelodysplastic rheumatology syndrome activation algorithm antibody arteritis autoimmune bacilliformis bartonella
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... peripheral blood leukocytes ... on the left Myeloblast ... Degree of bandemia ... #CBC #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... megaloblastic anemia ... #diagnosis #management ... #treatment #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Autoimmune Hemolytic Anemia ... • Anemia: macrocytic ... Autoimmune #Hemolytic #Anemia ... #diagnosis #management ... #treatment #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Treatment: ... #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... decreased PLT count: CBC ... PLT in selected cases ... changes), high MCV anemia ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... marrow failure with anemia ... Leukemia #oncology #hematology ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Blasts > 10% leukocytes ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... result in severe anemia ... immune hemolytic anemia ... from ischemia WBC ... #Workup #Hematology
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