40 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... -> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... of Chronic Disease ... Classification #Differential ... Diagnosis #Algorithm #Causes
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... peripheral blood leukocytes ... on the left Myeloblast ... Neutrophil (Normal) Differential ... #differential #
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... Polycythemia Vera • Chronic ... : • Acute or Chronic ... Iron deficiency anemia
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... - Differential ... malignancies • Anemia ... hemorrhage) • Chronic ... #Diagnosis #Causes
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Classification #Approach #Differential ... Diagnosis #Algorithm #Causes
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... Myelofibrosis • Chronic ... Thrombocytosis #Differential ... #Diagnosis #causes
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm
Pericardial
 • Effusion
 • Cardiac Tamponade*
 • Constriction
Myocardial
 •
Causes of Chronic ... Dyspnea - Differential ... Pulmonary - Other • Anemia ... Metabolic Acidosis #Chronic ... #Dyspnea #SOB #Differential
Causes of Wide Pulse Pressure - Differential Diagnosis
Physiologic:
 • Advanced age-arteriosclerosis (less compliant arteries)
 • Well
Causes of Wide Pulse ... Pressure - Differential ... disorders - Chronic ... Pulse #Pressure #Differential ... #Diagnosis #causes
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
of chronic inflammation ... of chronic kidney ... of chronic inflammation ... morphologic #mcv #differential ... #diagnosis #causes