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diagnosis causes generalized management pancytopenia pruritus secondary syndrome systemic workup aplastic blood cancer clinical cutaneous deficiency disorders elevatedmcv ferritin iron
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - ... cytopenias (usually anemia ... #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... just beneath the skin ... single-lineage dysplasia ... blood count with differential ... #hematology #oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... • Hypocellular myelodysplastic ... syndrome (MDS) ... Hypocellular/Hypoplastic MDS ... #oncology #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... - Amy Chung, MD ... Blood #Disorders #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD ... #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5. ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Hematology
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