24 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - ... Reactive: • Anemia ... /blood loss (Fe ... Chronic Myeloid Leukemia ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B lineage ... ALL is of B-cell lineage ... basophilia, and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... a.k.a Reactive Thrombocytosis ... malignancies • Anemia ... Chronic myeloid leukemia ... Diagnosis #Causes #hematology
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... these blasts is a linear ... acute myelogenous leukemia ... Path #BloodSmear #Blood
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... hematologic: Acute blood ... hemolysis, deficiency anemia ... Rebound effect from treatment
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... monoblast, & lymphoid lineages ... defined as white blood ... in peripheral blood ... the margins of blood
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Pelger-Huet, Macrocytic anemia ... PV), Essential Thrombocytosis ... @AmyChung #Blood ... #Disorders #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... to MDS or acute leukemia ... diagnosis #management #treatment ... #hematology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... hospitalization and treatment ... her peripheral blood ... maturation, and mixed lineage ... Path #BloodSmear #Blood