16 results
hematology diagnosis oncology differential algorithm causes aplastic chronic cll lymphocytic mds myelodysplastic platelets apl auer auerrods bandemia bloodsmear cancer cbc
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Reactive: • Anemia ... /blood loss (Fe ... Chronic Myeloid Leukemia ... causes #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Lymphocytes - T or B lineage ... ALL is of B-cell lineage ... basophilia, and thrombocytosis ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... hematologic: Acute blood ... hemolysis, deficiency anemia ... Rebound effect from treatment
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... to MDS or acute leukemia ... #diagnosis #management ... #treatment #hematology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... hospitalization and treatment ... her peripheral blood ... maturation, and mixed lineage ... Path #BloodSmear #Blood
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 Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... cytopenias (usually anemia ... transformation to acute leukemia ... only curative treatment ... #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hematopoiesis cell lineages—erythrocytic ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... syndromes with single-lineage ... Syndromes #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology ... hemeonc #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
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