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diagnosis hematology causes algorithm management thrombocytopenia anemia bruising workup atlas hemolytic nomenclature oncology pediatrics peds petechiae product reactions rheumatology thrombocytosis
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Diagnosis Platelet ... Reactive: • Anemia/blood ... Myelofibrosis • Chronic Myeloid ... Diagnosis #causes #Platelets ... #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... Von Willebrand Disease ... #disorders #hematology ... #hemepath #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... Thrombocytopenia • Platelet ... : Platelet Defects ... #Differential #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Connective Tissue Disorders
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Thrombocytopenia and Platelet ... Disorders - Differential ... History: - Prior platelet ... Thrombocytopenia #Platelet ... #Disorders #Differential
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... disorder Clinical ... Laboratory • Normal platelet ... VonWillebrand #Disease ... #Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... hematologic: Acute blood ... Vasculitides, IBD, Celiac disease ... Thrombocytosis #Platelets
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
of extravasated blood ... collection of blood ... lowest levels Platelet ... ability to bind platelets ... VWF:RCo/VWF:Ag (differentiate
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders ... - Differential ... ASanchez_PS #Platelet ... #Disorders #Differential ... #Diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
in Children Platelet ... - Increased platelet ... Hypersplenism - Impaired platelet ... Drug-induced Platelet ... count normal - Platelet
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