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diagnosis hematology anemia causes clinical hemolytic monoclonal myelodysplastic agglutinin classification cutaneous elevatedmcv focal gammopathy localized lymphadenopathy macrocytic macrocytosis manifestations mcv
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... ) - Differential ... Ig deposition disease ... Diagnosis #hematology ... #oncology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
syndrome • Myeloid ... appearing during the disease ... #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • Heavy Chain disease ... anemia due to cold ... #Monoclonal #Differential ... #Diagnosis #Oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Thalassemia • Lead ... Hypothyroidism • Myelodysplasia ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
(CAD) 2. ... younger pts) Differential ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Formation • Multiple Myeloma ... Dysplastic • Myelodysplastic ... #Causes #Hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Diagnosis Algorithm ... • Kikuchi Disease ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... nucleotidase deficiency, lead ... Agglutination - Cold ... #workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... Myeloproliferative Disease ... compounds, alcohol, lead ... blood count with differential ... #oncology
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