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diagnosis cutaneous gammopathy manifestations myelodysplastic skin agglutinin algorithm anemia causes cell disease hemolytic lymphadenopathy management mds mgus myelodysplasia paraproteinemias plasmacytoma
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Manifestations of Monoclonal ... cryoglobulinemia, Cold ... Scleromyxoedema, Acquired ... manifestations #dermatology ... #skin #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... capillary leak syndrome ... #Diagnosis #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphocytes) - Monoclonal ... Lymphadenopathy #LAD ... Algorithm #Causes #Hematology ... #Oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
angioedema • vWD • acquired ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... lymphoma, multiple myeloma ... assist device (LVAD ... Management #treatment #hematology ... #differential
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... • Myeloid hemopathy ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... compounds, alcohol, lead ... blood count with differential ... #diagnosis #hematology ... #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... tissue composed of monoclonal ... • Multiple myeloma ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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