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causes clinical generalized mds monoclonal pruritus secondary anemia apml cancer cutaneous differentiation elevatedmcv gammopathy macrocytic macrocytosis manifestations mgus myelodysplasia paraproteinemias
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
associated with myelodysplastic ... syndrome • Myeloid ... #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... Throbocythemia • Myelodisplastic ... syndrome Psychiatric ... #generalized #dermatology ... Diagnosis #Algorithm
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Formation • Multiple Myeloma ... Syndromes Macrocytosis ... #Diagnosis #Algorithm ... #Causes #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic ... , or all three myeloid ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... syndrome Psychiatric ... Pruritus #secondary #systemic ... #generalized #dermatology ... Diagnosis #Algorithm
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... initiation • Differential ... #management #hematology ... #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic ... evolution to acute myeloid ... median age at diagnosis ... cardiovascular or pulmonary ... #algorithm #hematology
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