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algorithm causes hemolytic leukemia monoclonal agglutinin atlas basophilia blood bloodcell chronic cll cold disease elevatedmcv gammopathy gap globulin hodgkins lymphocytic
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Myeloproliferative Disorders ... : • Chronic myeloid ... translocation • Acute myeloid ... #hematology #basophils
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... Pelger-Huet, Macrocytic anemia ... #hematology #Markers ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... Chronic inflammatory disorders ... MF) • Chronic myeloid ... #hematology #secondary
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... thalassemia, S Lepore • Basophilic ... Consider RBC membrane disorder ... #workup #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Unstable hemoglobin disorders ... lymphoma, Multiple myeloma ... lymphoma, Multiple myeloma ... RBC #Morphology #differential ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... AML (Acute Myeloid ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... • Small Bowel Disorder ... Formation • Multiple Myeloma ... Macrocytosis, Target Cells ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Diagnosis Algorithm ... #Classification ... #pathophysiology ... #Hematology #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
malignancies - B-cell ... younger pts) Differential ... , Myeloma • Waldenström ... sensitize red blood cells ... #hematology #diagnosis
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