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diagnosis hematology oncology syndrome algorithm anemia mds neurology thrombocytosis aplastic basophilia basophils cancer gbs guillain hodgkins immune infarction inflammatory iris
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... Thrombocytosis): • Acute infection ... vera (PV) • Myelodysplastic ... MF) • Chronic myeloid
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... deficiency) • Infection ... Myelofibrosis • Chronic Myeloid ... #Diagnosis #causes ... #Platelets #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Disorders: • Chronic myeloid ... translocation • Acute myeloid ... #Diagnosis #causes ... #hematology #basophils
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Summary myelo ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... #treatment #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Inflammation, Chronic Infection ... Hypothyroidism • Myelodysplasia ... #Anemia #MCV #Classification ... #Hematology
Causes of Splenic Infarcts - Differential Diagnosis • Myeloid disorders: Myeloproliferative neoplasms (myelofibrosis, polycythemia vera, essential
Causes of Splenic ... Infarcts - Differential ... Diagnosis • Myeloid ... thrombocythemia), Myelodysplastic ... endocarditis, Infectious
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... , or all three myeloid ... Out Secondary Causes ... • Parvovirus infection ... blood count with differential
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... to a preceding infection ... directed towards the myelin ... Syndrome #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Idiopathic • Infections ... • Hypocellular myelodysplastic ... CMV) • Epstein-Barr ... #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... causes need to ... vaccination - Myelin ... Myelitis #diagnosis #management ... #neurology #differential
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