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differential oncology mds myelodysplastic syndrome activation algorithm aplastic arterial blood dermatology dic disseminated embolism essential et hemeonc heparin hit intravascular
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
effect following treatment ... following EtOH induced ... thrombocytopenia ... Iron deficiency anemia ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... : - Drug induced ... - Hemolytic anemia ... #hematology #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Treat primary cause ... #diagnosis #causes ... #treatment #management ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ( ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Heparin Induced ... ) after 5-10d, venous ... ♀, ↑Age, ESRD Pathophysiology ... #Diagnosis #Management ... #Treatment #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
thrombocytopenia ... intravascular coagulation ... and other causes ... #Arterial #pathophysiology ... #hematology #differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
infections/fevers • Thrombocytopenia ... and petechiae Causes ... Treatment: ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... , or all three myeloid ... IDUS) • Immune Thrombocytopenia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Sepsis • Drug-induced ... with leukopenia, anemia ... , and thrombocytopenia ... #Management #Hematology ... #Rheumatology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Hydroxyurea + anticoagulation ... (if history of venous ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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