414 results
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... POEMS syndrome, myeloma ... Charcot-Marie-Tooth, Fabry's disease ... Peripheral #Neuropathy #differential ... diagnosis #causes #neurology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... vasculitis • Hematologic ... criteria for 1) hematologic ... conditions - multiple myeloma ... peripheral blood myeloid
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Hypercalcemia - Differential ... VitD: Multiple Myeloma ... Granulomatous diseases ... Hypercalcemia #Differential ... Algorithm #Workup #nephrology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Myelofibrosis • Chronic Myeloid ... Thrombocytosis #Differential ... causes #Platelets #hematology
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma ... Newly Diagnosed Myeloma ... Newly Diagnosed Myeloma ... Treatment #Algorithm #management ... #hematology #oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Disorders: • Chronic myeloid ... Colitis and Crohn’s Disease ... #Basophilia #Differential ... Diagnosis #causes #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... lymphoma, multiple myeloma ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... disorders • Celiac disease ... Non malignant hematologic ... states • Non-hematologic ... Thrombocytosis #Differential
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
Intrinsic Renal Disease ... - Differential ... Fibromuscular disease ... Cast nephropathy (myeloma ... #nephrology #differential