118 results
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
Secondary Causes ... SCD, leukemia, myeloma ... or are zebras (…amyloid ... Diagnosis #Management #Urology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
POEMS syndrome, myeloma ... , secondary amyloid ... differential #diagnosis #causes ... #neurology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... ): - Amyloid precursor ... Down syndrome (amyloid ... seizure, primitive reflexes
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Amyloidosis: • Primary amyloid ... Bone/Joint: • Amyloid ... (AMYLOID ANGIOPATHY ... Protein • AL Amyloid ... hypoadrenalism • Nausea
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Myelofibrosis • Chronic Myeloid ... Differential #Diagnosis #causes
Bell's palsy
There are many different causes of Facial Nerve Palsy. However, the commonest
cause of unilateral facial
many different causes ... the commonest cause ... Loss of Corneal Reflex ... #Bells #Palsy #Neurology
What's in a Fibril?
Amyloid 8-12 nm Congo Red + Randomly arranged 
Fibrillary GN 12-20 nm Congo
Amyloid 8-12 nm ... #fibrils #nephrology ... #diagnosis #amyloid
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Disorders: • Chronic myeloid ... translocation • Acute myeloid ... Chickenpox Other Causes ... Differential #Diagnosis #causes
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
• Acute Myeloid ... • Chronic Myeloid ... endocrinology #causes
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... of acute myeloid