38 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lymphocytes) - Monoclonal ... Reed-Sternberg Cells ... #Causes #Hematology ... #Oncology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Diagnosis Platelet ... Non-infectious (malignancy, rheumatologic ... Myelofibrosis • Chronic Myeloid ... Leukemia - BWH ... #Diagnosis #causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Management Summary myelo ... = funny-shaped cells ... old, ~10,000 new cases ... transformation to acute leukemia ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... (myeloid)↑ • Mature ... -> AML: Blast crises ... #Hematology #Oncology ... #Diagnosis
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Diagnosis Framework ... total white blood cell ... similarly to mast cells ... #Diagnosis #causes
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... Diagnosis Algorithm ... • Neoplastic (Leukemia ... #Causes #Hematology ... #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... marrow plasma cell ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Significance #MGUS #Differential ... #Diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Transformation to large cell ... fludarabine) 3) Monoclonal ... #oncology #hematology ... #hemeonc #diagnosis