17 results
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lymphocytes) - Monoclonal ... Reed-Sternberg Cells ... #Causes #Hematology ... #Oncology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... - Differential ... • Neoplastic (Leukemia ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... (myeloid)↑ • Mature ... -> AML: Blast crises ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Exam/Signs: • Lymphadenopathy ... Diagnosis: • ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Transformation to large cell ... fludarabine) 3) Monoclonal ... #oncology #hematology ... #hemeonc #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Management Summary myelo ... = funny-shaped cells ... old, ~10,000 new cases ... transformation to acute leukemia ... #hematology #oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... Diagnosis Framework ... total white blood cell ... similarly to mast cells ... #Diagnosis #causes
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... marrow plasma cell ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
hyperviscosity, lymphadenopathy ... marrow plasma cells ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... (NHL) ~60% - lymphadenopathy ... Responsive to Treatment ... Treated Like Acute Leukemias ... #differential #