21 results
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
common in IgM gammopathy ... formation #IgM #gammopathy ... #MGUS #Clinical ... #Pathology #Hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Features: POEMS, AL amyloid ... deposits: Ig-related amyloid ... #Significance #MGUS ... Differential #Diagnosis #hematology
MGRS - Monoclonal Gammopathy of Renal Significance 

#MGRS #Monoclonal #Gammopathy #Renal #Significance #Diagnosis #Pathology
MGRS - Monoclonal ... Gammopathy of Renal ... Significance #MGRS ... #Monoclonal #Gammopathy ... Significance #Diagnosis #Pathology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
with monoclonal gammopathy ... , low-risk MGUS ... concerning for myeloma ... #monoclonal #gammopathy ... diagnosis #management #hematology
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
of monoclonal gammopathy ... significance (MGUS ... #monoclonal #gammopathy ... #MGUS #Followup ... diagnosis #management #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... Summary Framework Hematologic ... to IgM multiple myeloma ... to light-chain myeloma ... #Monoclonal #Gammopathy
Amyloidosis Diagnosis
1) Patient presentation
 • Cardiac-specific signs of amyloidosis: Diastolic heart failure, Heart failure with preserved
diarrhea, Monoclonal gammopathy ... significance (MGUS ... neuropathy, atypical MGUS ... or smoldering myeloma ... 2) Methods of amyloid
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... AML #Clinical #Hematology ... #Pathology #Smear
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... conditions - multiple myeloma ... peripheral blood myeloid ... cells NEJM Review
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
of Monoclonal Gammopathy ... Significance (MGUS ... glycoprotein (MAG) in myelin ... #Monoclonal #Gammopathy ... Complications #diagnosis #hematology