14 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... syndrome (MDS) ... syndrome (MDS) ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... , Myelodysplastic ... syndrome, Increased ... uremic syndrome ... #differential #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... , MDS, Chemotherapy ... lymphoma, Multiple myeloma ... lymphoma, Multiple myeloma ... differential #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - ... Summary myelo ... #Syndrome #MDS ... Management #treatment #hematology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... platelets) • MDS ... , or all three myeloid ... Myeloproliferative Disease ... #hematology #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Disorders - Markers and ... Disorders - Myelodysplastic ... Disorder - Abnormal morphology ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Formation • Multiple Myeloma ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... • Rule out B12 and ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• Hypocellular myelodysplastic ... syndrome (MDS) ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... #oncology #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... 40 ml/min A - Anemia ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology