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diagnosis management algorithm causes workup leukemia signs symptoms dermatology monoclonal myelodysplastic pancytopenia arthritis atlas chronic cll erythematosus hemeonc hemolysis hemolytic
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... thromboembolic disease ... Abnormalities: macrocytic anemia ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk #MultipleMyeloma
active multiple myeloma ... CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... Hypercalcemia #Anemia ... #Clinical #Diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... lymphoma, Multiple myeloma ... lymphoma, Multiple myeloma ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Formation • Multiple Myeloma ... Myelodysplastic Syndromes ... • Liver Disease ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... Myelodysplastic syndrome ... MF) • Chronic myeloid ... Diagnosis #Causes #hematology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
• Myeloid hemopathy ... appearing during the disease ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... capillary leak syndrome ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... other forms of myeloma ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
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