26 results
diagnosis differential rheumatology management symptoms dermatology leukemia monoclonal abnormal algorithm cutaneous hepatology manifestations mgus myelodysplastic workup agglutinin alzheimersdisease anemia arthritis
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... thromboembolic disease ... vasculitis • Hematologic ... cells NEJM Review
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... • Myeloid hemopathy ... appearing during the disease ... differential #diagnosis #dermatology ... #oncology #clinical
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... osteolytic lesions and pathologic ... Diagnosis #Management #oncology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... other forms of myeloma ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... capillary leak syndrome ... Ig deposition disease ... Differential #Diagnosis #hematology ... #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... ULN R - Renal disease ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... mutations - Down syndrome ... chromosome 21) Signs ... geriatrics #diagnosis #signs
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... Vasculitis #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical ... manifestations #pathology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... and hepatorenal syndrome ... • Budd Chiari syndrome ... • Infiltrative diseases ... Veno-occlusive disease
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