26 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... thromboembolic disease ... vasculitis • Hematologic ... cells NEJM Review
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... other forms of myeloma ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Eosinophilia and Systemic Signs ... (DRESS Syndrome ... #Dermatology #SkinRash ... #DRESS #Syndrome ... Eosinophilia #Legs #Photo
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Eosinophilia and Systemic Signs ... (DRESS Syndrome ... #Dermatology #SkinRash ... #DRESS #Syndrome ... Eosinophilia #Photo
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... • Myeloid hemopathy ... appearing during the disease ... differential #diagnosis #dermatology ... #oncology #clinical
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... osteolytic lesions and pathologic
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... mutations - Down syndrome ... chromosome 21) Signs ... geriatrics #diagnosis #signs
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... capillary leak syndrome ... • Schnitzler syndrome ... Ig deposition disease ... Differential #Diagnosis #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... Vasculitis #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical ... manifestations #pathology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... and hepatorenal syndrome ... • Budd Chiari syndrome ... • Infiltrative diseases ... Veno-occlusive disease