970 results
Therapeutic Plasma Exchange - Circuit Diagram
Goal = removal of abnormal/excess cells or substances that:
 • Have
Cryoglobulin • Myeloma ... Plasma #Exchange #pathophysiology
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
: • Multiple myeloma ... Differential #Diagnosis #Pathophysiology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
) - Multiple myeloma ... deficiency #Ammonia #Pathophysiology
Acquired Disorders of Reduced Bone Strength: Pathogenesis
 • Hyperparathyroidism
 • Vitamin D deficiency
 • Malabsorption syndromes
., multiple myeloma ... #BoneStrength #pathophysiology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
DNA, RNA, and myelin ... #Pathophysiology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
pathway -> Decreased myelin ... Differential #Diagnosis #Pathophysiology
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
SCD, leukemia, myeloma ... or are zebras (…amyloid
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
directed towards the myelin ... the underlying pathophysiology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... activation -> diffuse myelin
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
POEMS syndrome, myeloma ... , secondary amyloid