26 results
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
onset of muscle symptoms ... , hypothyroid-induced ... syndrome (GBS), ... antisynthetase syndrome ... Lambert-Eaton myasthenic syndrome
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... reflexes, Anaemia #Hypothyroid
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Hypothyroid Myopathy ... Symmetric, proximal myopathy ... Rhabdomyolysis (rare) #Hypothyroid ... #Myopathy #pathophysiology ... #signs #symptoms
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... varied clinical symptoms ... There are several symptoms ... Myopathy due to ... endocrinology #hypothyroid
Causes of Back Pain - Differential Diagnosis Algorithm
Always assess for red flags. If no red flags,
constitutional symptoms ... Unresolved Radicular Symptoms ... • Cauda Equina Syndrome ... Spondyloarthropathies • Myelopathic
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. 

Source:  Does This
Acute Coronary Syndrome ... Likelihood Ratios for Symptoms ... Acute Coronary Syndrome ... EBM #Diagnosis #Cardiology ... AcuteCoronarySyndrome #Symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... less systemic symptoms ... anti-synthetase syndrome ... and anti-HMGCR myopathy
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... proximal weakness Myopathy ... Endocrinopathies: Hypothyroid
LUMBAR Syndrome

What do you call a segmental lumbosacral hemangioma + spinal problems?? LUMBAR syndrome, a fairly
LUMBAR Syndrome ... LUMBAR syndrome, ... vascular anomaly syndrome ... & Ulceration Myelopathy ... #Radiology #Diagnosis
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. Source: Fanaroff AC, Rymer
Acute Coronary Syndrome ... Likelihood Ratios for Symptoms ... Acute Coronary Syndrome ... EBM #Diagnosis #Cardiology