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diagnosis differential neurology signs symptoms management syndrome algorithm behavioraldisorder pharmacology clinical complications endocrinology msk nutrition sideeffects treatment barre bulimianervosa caudaequina
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... (Also caused by ... Complications #pathophysiology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... #differential #causes
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm With Sensory Changes:
Causes of Peripheral ... Weakness - With ... • No Objective Weakness ... Oculomotor • Myopathy ... Diagnosis #Algorithm #Causes
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Elevation (Pain > Weakness ... Subacute to Chronic Causes ... (Weakness > Pain ... PROXIMAL MUSCLE WEAKNESS
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Weakness without ... No Objective Weakness ... • Congenital Myopathy ... Diagnosis #Algorithm #Causes
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Mitochondrial myopathy ... Neuromuscular #Weakness ... #Causes #differential
Benzodiazepines: Mechanism of Action and Side Effects • Decr spinal cord activity -> Muscle relaxant
slurred speech, weakness ... Benzodiazepines #Psychiatry ... #Pharmacology #pathophysiology
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness ... I am weak": • Myopathy ... #Generalized #Weakness ... Differential #Diagnosis #causes
Causes of Falls in the Elderly - Differential Diagnosis Algorithm - Intrinsic Factors - Presyncope / Syncope
Causes of Falls ... Neurological / Psychiatric ... Performance Measures • Weakness ... Diagnosis #Algorithm #Causes
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Tiring easily/weakness ... Bone/joint pain Psychiatric ... Secondary #Tertiary #pathophysiology
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