29 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Cord: Demyelinating ... heavy metals), Critical ... Mitochondrial myopathy
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
gain, Anorexia, Cold ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... Symptoms #Diagnosis #PhysicalExam
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... IU/I • SAMS clinical
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... Causes of spinal ... • Extrinsic Causes ... • Intrinsic Causes ... - Radiation myelopathy
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... immobility • Critical ... Illness Myopathy ... - Inflammatory myopathy ... polymyositis, necrotizing myopathy
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Causes: 1. ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... : CHF, valves, COPD ... I am weak": • Myopathy ... Rhabdomyolysis, Critical ... Differential #Diagnosis #causes
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness without ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... Diagnosis #Algorithm #Causes
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
syndrome resulting ... and scaly skin, myopathy ... Myopathy due to ... reflex hammer, caused ... Hypothyroidism #PhysicalExam
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... of the spinal cord ... Paraneoplastic syndrome ... Myopathy: ... mediated necrotizing myopathy