15 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... 80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... (Also caused by
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... systemic lupus erythematosus ... antisynthetase syndrome
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Weakness without ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... Diagnosis #Algorithm #Causes
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Myalgia, Muscle weakness ... of movement, Deafness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... Symptoms #Diagnosis #PhysicalExam
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... and scaly skin, myopathy ... Myopathy due to ... reflex hammer, caused ... Hypothyroidism #PhysicalExam
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
Upper Extremity Dermatomes ... hand" ± Horner Syndrome ... Carpal Tunnel Syndrome ... anesthesia and deltoid weakness ... sensory #motor #arm #physicalexam
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Aseptic Meningitis, Myelopathy ... autoantibodies that will cause ... Systemic #Lupus #Erythematosus
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
Lower Extremity Dermatomes ... • Cauda Equina Syndrome ... Commonly caused ... claudication and weakness ... sensory #motor #leg #physicalexam
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
• Thiamine - Nausea ... ataxia), Korsakoff syndrome ... cognitive deficits, myelopathy ... diarrhea • Copper - Myelopathy ... with muscle weakness