14 results
diagnosis differential erythematosus myopathy sle systemic management myositis vasculitis autoimmune myopathies treatment cerebritis cns comparison complications cryoglobulinemia cryoglobulins dermatology hematology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
symmetric muscle weakness ... symmetric muscle weakness ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... 80%) - Proximal Weakness ... femoral heads • Myopathy ... #Systemic #Lupus ... Complications #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Aseptic Meningitis, Myelopathy ... Disease, PRES Pathophysiology ... CNS #neurology #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... have significant weakness ... Myositis #diagnosis #rheumatology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... GBS), systemic lupus ... antisynthetase syndrome
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... Churg-Strauss syndrome ... - systemic lupus ... dermatomyositis #Size #Classification ... Vessels #Diagnosis #Rheumatology
NPSLE - Neurological and Psychiatric Manifestations of Systemic Lupus Erythematosus • Central: Aseptic meningitis, Cerebrovascular disease,
Manifestations of Systemic Lupus ... Demyelinating syndrome ... Seizure disorder, Myelopathy ... Guillain-Barre syndrome ... Erythematosus #SLE #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... purpura, Arthralgia, Weakness ... (e.g. systemic lupus ... diagnosis #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Non-autoimmune rheumatologic ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... Erythematosus #Diagnosis #Rheumatology
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
RASH + MUSCLE WEAKNESS ... Any inflammatory myopathy ... antisynthetase syndrome ... Severe proximal weakness ... IIMs #diagnosis #rheumatology
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