27 results
diagnosis differential neurology clinical management myositis algorithm causes erythematosus lupus myopathies signs sle symptoms systemic autoimmune comparison cord endocrinology hematology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
rimmed vacuoles HIV myopathy ... load Drug-induced myopathy ... Gemcitabine Lupus Myopathy ... 5-15% of lupus myopathy ... diagnosis #comparison #rheumatology
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... Myopathies #Idiopathic #Myopathy ... Managment #algorithm #Rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... and anti-HMGCR myopathy ... Myositis #diagnosis #rheumatology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... • Inflammatory myopathy ... Guillain-Barré syndrome ... antisynthetase syndrome
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... Complications #pathophysiology
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Myalgia, Muscle weakness ... Psychosis, Deafness ... of movement, Deafness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Any inflammatory myopathy ... antisynthetase syndrome ... Inflammatory myopathy ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy ... Neuromuscular #Weakness
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
of Peripheral Weakness ... No Objective Weakness ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Peripheral #Weakness
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... clinical #diagnosis #rheumatology
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