23 results
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. 

Source:  Does This
Acute Coronary Syndrome ... Acute Coronary Syndrome ... EBM #Diagnosis #Cardiology ... #ACS #AcuteCoronarySyndrome ... #Symptoms #Signs
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... antisynthetase syndrome ... myopathies such as
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Motor Nerves: ALS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... Complications #pathophysiology ... #signs #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... less systemic symptoms ... anti-synthetase syndrome ... have significant weakness
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. Source: Fanaroff AC, Rymer
Acute Coronary Syndrome ... Likelihood Ratios for Symptoms ... Acute Coronary Syndrome ... EBM #Diagnosis #Cardiology ... #ACS #AcuteCoronarySyndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... have fever - ACS ... : • Pathophysiology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... /paralysis - Weakness ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... Upper extremity weakness ... anesthesia. leg weakness ... #diagnosis #pathophysiology ... #signs #symptoms