46 results
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... cord - Signs and Symptoms ... • Gross motor weakness ... diagnosis #signs #symptoms ... #msk
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
Symptoms of Hypophosphatemia ... Bone pain • MSK ... : Proximal myopathy ... Diaphragmatic weakness ... Hypophosphatemia #Phosphate #Symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... antisynthetase syndrome ... Lambert-Eaton myasthenic syndrome
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... 10%) - Proximal Weakness ... femoral heads • Myopathy ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... Mitochondrial myopathy ... #Causes #differential
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... less systemic symptoms ... anti-synthetase syndrome ... have significant weakness
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... Sensory Changes - Differential ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Neurology #Differential
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome ... diagnosis #neurology #differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... • Acute stroke syndromes ... Paraneoplastic syndrome ... Myopathy: ... #Differential #