24 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... femoral heads • Myopathy ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... any time during treatment ... symmetric muscle weakness ... Guillain-Barré syndrome ... antisynthetase syndrome
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... anti-synthetase syndrome ... have significant weakness ... after 2 years of treatment
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper extremity weakness ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... Mitochondrial myopathy ... differential #diagnosis #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
findings: • Symptoms ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... varied clinical symptoms ... There are several symptoms ... characterized by muscle weakness ... clinical #video #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... spine Signs / Symptoms ... Complications: • Weakness ... #MSK #pathophysiology ... #diagnosis #symptoms
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... - Radiation myelopathy ... differential #diagnosis #neurology