31 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... anti-synthetase syndrome ... /full triad at diagnosis ... #rheumatology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Symptoms: Tiredness ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... #Diagnosis #PhysicalExam
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... Atorvastatin Diagnosis ... #diagnosis #management
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
- Differential Diagnosis ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Neurology #Differential ... #Diagnosis #Algorithm
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Guillain-Barre syndrome ... Mitochondrial myopathy ... #differential #diagnosis ... #neurology
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... varied clinical symptoms ... characterized by muscle weakness ... Hypothyroidism #PhysicalExam ... clinical #video #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome ... #neurology #differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... • Acute stroke syndromes ... Paraneoplastic syndrome ... #Differential #Diagnosis ... #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Lower motor neuron symptoms ... - Radiation myelopathy ... #differential #diagnosis ... #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Progressive muscle weakness ... Progression of weakness ... , Mild sensory symptoms ... persistent asymmetry of weakness ... #neurology #neuropathy