74 results
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... or peripheral neurologic ... mimics #diagnosis #differential ... #causes #neurology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Symptoms: Tiredness ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Neurology #Differential
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
Causes of Peripheral ... Sensory Changes - Differential ... Oculomotor • Myopathy ... #Sensory #Neurology ... #Differential #
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Mitochondrial myopathy ... #Causes #differential ... #diagnosis #neurology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... and signs below ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... femoral heads • Myopathy ... (Also caused by ... pathophysiology #signs ... #symptoms #diagnosis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... • Acute stroke syndromes ... Lack of UMN/LMN signs ... #Differential # ... Diagnosis #neurology
Causes of Back Pain - Differential Diagnosis Algorithm
Always assess for red flags. If no red flags,
Causes of Back Pain ... - Differential ... constitutional symptoms ... • Cauda Equina Syndrome ... Spondyloarthropathies • Myelopathic