55 results
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Treatment of Wilson's ... Disease • D-penicillamine ... Tetrathiomolybdate - Aims ... copper #Wilsons #Disease ... #Treatment #management
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Krabbe Disease ... case of Krabbe disease ... testing and expedite treatment ... failure, cerebellar ataxia ... MarkMamloukMD #Krabbe #Disease
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Presentation: • Mild disease ... Meningitis • Weil's Disease ... Severe pulmonary disease ... ARDS Diagnosis ... microbiology #diagnosis #treatment
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Motor dysfunction: myoclonic ... incontinence, apraxia
Lyme Disease Pearls

Epidemiology: Ixodes scapularis carrying borrelia 
have spread and are now found in 
growing areas
Lyme Disease Pearls ... Slovenia) Treatment ... : TREATMENT Shorter ... doxycycline in kids
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
Treating Chagas Disease ... Trypanosomiasis) in HIV-AIDS ... duration same as for treatment ... Note: Treatment ... IDSA #Prevention #Treatment
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Inflammatory bowel disease ... dental fixatives, Treatment ... of Wilson's disease ... Metabolic: Menkes disease ... Optic neuropathy, Ataxia
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
di-basic amino acids ... recessive genetic disease ... - Antiviral treatment ... herpes virus or HIV/AIDS
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... kidneys, liver, lung/ARDS ... necrosis STSS Treatment ... BIDMC Infectious Diseases ... Syndrome #STSS #treatment
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfusion • Criteria: ARDS ... other cause of ARDS ... : 33% • Treatment ... elevated BNP, high CVP ... : No • Treatment