17 results
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... transient hemolysis • Treatment ... Plasmapheresis - VA ... Hemolytic #Anemia #hematology
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
travel, animal exposure ... differential: basal cell ca ... squamous cell ca ... Blastomycosis #SkinRash #dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Puncture, EEG Treatment ... prevention (statin for CVA ... CNS #neurology #rheumatology ... diagnosis #management #treatment
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
Tissue Factor exposure ... complexes with FVa ... diagnosis #models #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... elevated BNP, high CVP ... : No • Treatment ... Transfusion #Reactions #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Careful enquiry of exposure ... non-essential drug/HDS treatments ... Diagnosis #Algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Procoagulant Exposure ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
predominance) • CANOMAD (Ataxia ... Scleromyxedema (CNS+GI+CVS ... • Amyloidosis (CVS ... Paraproteinemias #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
reverse any warfarin exposure ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
older adults • Exposure ... microglobulin Treatment ... workup #oncology #hematology