22 results
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... (ASS), Inclusion ... Body Myositis (IBM ... #Idiopathic #Myopathy
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... such as • Statin-induced ... myopathy (SAMS) ... Atorvastatin Diagnosis ... #diagnosis #management
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... Body Myositis (IBM ... MSAs #clinical #diagnosis ... #rheumatology #table
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. 

Source:  Does This
Acute Coronary Syndrome ... - Diagnostic Likelihood ... Acute Coronary Syndrome ... #EBM #Diagnosis ... #Cardiology #ACS
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... anti-synthetase syndrome ... /full triad at diagnosis ... and anti-HMGCR myopathy ... after 2 years of treatment
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. Source: Fanaroff AC, Rymer
Acute Coronary Syndrome ... - Diagnostic Likelihood ... Acute Coronary Syndrome ... #EBM #Diagnosis ... #Cardiology #ACS
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Cardiorenal Syndrome ... Type 3 - Acute RCS ... Hypertension, CKD induced myopathy ... #Cardiorenal #Syndrome ... #CRS #Types #cardiology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy ... #differential #diagnosis
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential Diagnosis ... Infectious: Influenza, EBV ... I am weak": • Myopathy ... Polyneuropathy, ALS ... #Differential #Diagnosis
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
acute coronary syndrome ... (ACS) evaluation ... Angina #ChestPain #Diagnosis ... Management #Algorithm #Cardiology ... #EBM #Trial