992 results
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Statin-Associated Muscle Symptoms ... onset of muscle symptoms ... Symptoms: • Proximal ... statin-associated muscle symptoms ... Muscle biopsy if symptoms
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
Symptoms of Hypophosphatemia ... MSK: Proximal myopathy ... Hypophosphatemia #Phosphate #Symptoms
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Hypothyroid Myopathy ... Symmetric, proximal myopathy ... #Hypothyroid #Myopathy ... pathophysiology #signs #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... less systemic symptoms ... and anti-HMGCR myopathy
Hyperthyroidism – symptoms and signs. 

Symptoms:

Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
Hyperthyroidism – symptoms ... Symptoms: Weight ... loss, Proximal myopathy ... Hyperthyroidism #Symptoms
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
varied clinical symptoms ... There are several symptoms ... and scaly skin, myopathy ... Myopathy due to
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... hypertrophy, Proximal myopathy ... Features #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
femoral heads • Myopathy ... pathophysiology #signs #symptoms
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
gain, Bruising, Myopathy ... Tumors #Signs #Symptoms
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Deficiency - Signs and Symptoms ... Hernias (CAH-X), Myopathy ... Deficiency #Signs #Symptoms