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diagnosis table associations diseases erythematosus lupus management systemic antibody antineutrophil antinxp2 antinxp2dm dermatology dermatomyositis disease igg4 phenotypes related sle treatment
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... #Antinuclear #Antibody ... #antibodies #diagnosis ... #rheumatology #
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... others (RNP, aPL antibodies ... Ill • ANCA Vasculitis ... : P-ANCA (perinuclear ... ), C-ANCA (cytoplasmic
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... Disease Associations ANA ... Graves' disease c-ANCA ... granulomatosis p-ANCA ... #antibodies
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... searched for when ANA ... #autoantibodies ... erythematosus #diagnosis #rheumatology ... #table #ANA
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
aorta • Head and ... pancreas, biliary, renal ... serum lgE, no autoantibodies ... (antinuclear antibodies ... workup #treatment #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... • Anti-Ro/SSA autoantibodies ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... • (-) ANA + (+
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Antibodies targeting ... dorsal part of the MCP ... • Clear cell renal ... diagnosis #management #rheumatology
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