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diagnosis erythematosus lupus management autoantibodies differential disease patterns sle table anca antibody antineutrophil arthritis associations diseases igg4 laboratory phenotypes related
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE), Sjogren's ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... scleroderma) - Anti-Scl ... 70% of cases • Sjögren ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... erythematosus (SLE), Sjogren's ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... Anticoagulant (LAC) • Sjogren ... • Scleroderma (Systemic ... Autoantibodies #Rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... (ANA) - 95% - Initial ... severe disease & renal ... heart block • Sjogren ... Summary #diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Sjogren Anti-SSB ... Associated with Sjogren ... erythematosus #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... enlargement Sjogren's ... ab • RF • Antinuclear ... antibodies ≥ 1: ... #Syndrome #Rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
female, asian • Systemic ... autoantibodies (antinuclear ... antibodies, rheumatoid ... management #phenotypes #workup ... #treatment #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... dermatomyositis, Sjogren ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... -70, RNP antibodies
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... erythematosus (SLE) - Antinuclear ... antibodies, which ... Arthritis #laboratory #workup
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