13 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... #Antinuclear #Antibody ... #antibodies #diagnosis ... #rheumatology #
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Testing - Nuclear ... #Antinuclear #Antibody ... #Testing #Nuclear ... differential #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... ARUPConsult @ARUPLabs #ANA ... #Testing #Nuclear ... differential #diagnosis #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
aorta • Head and ... pancreas, biliary, renal ... autoantibodies (antinuclear ... antibodies, rheumatoid ... workup #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... erythematosus (SLE) - Antinuclear ... antibodies, which ... - CCP antibody testing ... #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
smear, HIV/HCV testing ... function test, ANA ... anti-phospholipid antibodies ... changes), high MCV ... Causes #Workup #hematology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
- Fever >= 39C lasting ... Lymphadenopathy and ... rheumatoid factor or antinuclear ... antibodies Exclusion ... #Major #Minor #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
hypofunction • Antibodies ... examination Labs: • Antibodies ... ab • RF • Antinuclear ... antibodies ≥ 1: ... Sjogrens #Syndrome #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... La, anti-Jo-1, SCL ... -70, RNP antibodies ... anticardiolipin antibodies
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... Rh) & recipient antibodies ... , DIC, hypoTN, renal ... false negatives on testing ... diagnosis #management #hematology