11 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... dL the ULN R - Renal ... /dL or CC < 40 ml ... if this is is monoclonal ... MGUS #diagnosis #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... malignancy: • Symptoms ... : B-symptoms, bruising ... Labs: anemia, ↑ MCV ... #hematology #WBC
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... (HCV) • CLL & MBL ... Amyloidosis and monoclonal ... , retinal, DVT, ... Paraproteinemias #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Renal Disease, Liver ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
disease (panuveitis, retinal ... CNS symptoms (headache ... refractory disease : monoclonal ... management #signs #symptoms ... #rheumatology #
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... experience some symptoms ... than 150,000 per mcL ... than 4000 per ml ... /mean MCV) × 100
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... abnormal intact monoclonal ... constitutional symptoms ... hyperCalcemia, Renal ... #Significance #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Reticulocytosis • Renal ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Complications of Monoclonal ... treatment of infective symptoms ... ; vaccinations Renal ... disease - Monoclonal ... Complications #diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology