13 results
diagnosis hematology management differential mgus oncology cryoglobulinemia cryoglobulinemic gammopathy lupus sle vasculitis anca antibodies antibody antineutrophil antinuclear antinxp2 antinxp2dm behcet
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Monoclonal Gammopathies ... dL the ULN R - Renal ... /dL or CC < 40 ml ... if this is is monoclonal ... MGUS #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... (HCV) • CLL & MBL ... monoclonal fibrillary ... , retinal, DVT, ... Paraproteinemias #Hematology
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
cold temperature and ... arterioles) MONOCLONAL ... necrosis • Pain and ... arthritis • Renal ... Vasculitis #Diagnosis #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
disease (panuveitis, retinal ... involvement (uveitis or retinal ... Ocular: Giant retinal ... refractory disease : monoclonal ... signs #symptoms #rheumatology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... immunoglobulin is an ... hyperCalcemia, Renal ... with ratio >1.65 and ... #Significance #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... polyangiitis without renal ... Jcortesizaguirr #ANA ... antibodies #diagnosis #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... Combined decr of C3 and ... /min • <60 mL/ ... TerrierBen #Renal ... Vasculitis #Management #Rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... and probably < ... 1500ng/mL • Non-adherence ... Special cases (e.g. renal ... Measurement #SLE #rheumatology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
in non-muscle myosin ... renal failure ... vWF, factor V, and ... myelofibrosis and ... differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Serositis Labs: • ANA ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology
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