19 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Normal CK - Myositis ... Osteoporosis #Systemic ... #Lupus #Erythematosus ... pathophysiology #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... joints Nervous system ... Glomerulonephritis Myositis ... #erythematosus ... #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... Lupusreference #SLE #Systemic ... #Lupus #Erythematosus ... autoantibodies #signs
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
• Transverse myelitis ... positive NMO only): Myositis ... autoimmune disorders (Systemic ... lupus erythematosus ... neurology #symptoms #signs
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... SLE) - Typical Signs ... Arthralgia / arthritis, Myositis ... #Lupus #Erythematosus ... #SLE #Signs #Symptoms
Aortic Stenosis - Diagnosis and Stages

Clinical Presentation
- Exertional dyspnea
- Chest pain
- Palpitations
- HF Symptoms (orthopnea, PND,
- Late peaking systolic ... Diagnosis #Stages #Management ... #Signs #Symptoms ... #Cardiology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... syndrome (GBS), systemic ... lupus erythematosus ... inclusion body myositis ... myopathy #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... Conjunctivitis, mucositis ... central nervous system ... lupus erythematosus ... purpura: strong sign
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... pulse pressure: systolic ... echocardiography: identifies systolic ... heartfailure #diagnosis #management ... #cardiology #pharmacology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... neuritis • Partial myelitis ... • Lhermitte’s sign ... Signs and symptoms ... sclerosis #diagnosis #management