13 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... Sodium zirconium ... for hydrogen and sodium ... • Mechanism: Sodium-K ... #medications #pharmacology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Urologic irrigants Hypotonic ... > 30): SIADH, Medications ... Beer potomania Isotonic ... Algorithm #diagnosis #sodium
Drugs causing hyperkalemia
 • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly
 •
Drugs causing hyperkalemia ... Ketoconazole • Sodium ... Drospirenone #Drugs #hyperkalemia ... #medications #causes
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... (Heparin) • Sodium-channel ... MunerMohamed1 #hyperkalemia ... pharmacology #potassium #medications
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Insensible losses Sodium ... in kidneys) - Medications ... cisplatin) - Chronic hypercalcemia ... - Chronic hypokalemia
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Physiologic Approach to Hypotonic ... have a case of hypotonic ... : SIADH, Renal Sodium ... : Hypovolemia, Hypervolemia ... diagnosis #table #sodium
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... overdose) - Sodium ... panitumumab) #Drugs #hypokalemia ... hypomagnesemia #Medications
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... STOP offending medications ... (Bicarb≥22) or isotonic ... bradycardia • Isotonic
Treatment of Hyperkalemia
Membrane Stabilization
 • Calcium Gluconate (10%)
 • Hypertonic (3%) Normal Saline
Shifters:
 • Insulin (Short
Treatment of Hyperkalemia ... Furosemide • Sodium ... Bicarbonate • Sodium ... Hemodialysis #Hyperkalemia ... Management #Treatment #Medications
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Differential Algorithm Isotonic ... , Recent TURP Hypotonic ... polydipsia • Hypervolemia ... causes #nephrology #sodium